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Friday, March 29, 2013
Xbox SmartGlass Will Be Your BFF While Watching Game of Thrones
Thursday, March 28, 2013
Gay marriage equality box spreads on social media
NEW YORK (AP) ? Bud Light said it with beer cans and Martha Stewart with red velvet cake as companies and celebrities from Beyonce to George Takei joined millions of social media users in posting and tweaking a simple red logo in support of gay marriage.
A square box with thick pink horizontal lines (the mathematical equal symbol) was offered for sharing this week by the Human Rights Campaign as the U.S. Supreme Court took up arguments in key marriage rights cases.
The image, replacing profile pictures on Facebook, Twitter, Instagram, Tumblr, Pinterest and elsewhere, is a makeover of the advocacy group's logo, usually a blue background with bright yellow lines. The HRC made it available in red ? for the color of love ? on Monday and estimated tens of millions of shares by Wednesday.
"It shows the enthusiasm and the passion," said Fred Sainz, a spokesman for the nonprofit in Washington, D.C.
Like viral campaigns of yore, supporting breast cancer awareness (pink), President Barack Obama (change your middle name to Hussein) and even Arab Spring (green), a bit of fatigue set in on some social media streams by those questioning whether such efforts serve to change any minds or, put simply, are plain annoying.
"My Facebook feed is a cascading aesthetic nightmare. Thanks, equality," Washington Post writer Dan Zak wryly grumbled on Twitter.
A photo of Justice Anthony Kennedy made the rounds with the quip: "Before we make a ruling, did enough people change their Facebook profile picture?!"
None of that mattered to the masses of same-sex marriage supporters. Some swapped matzoh for the pink lines as Passover got under way, or added frowny Internet star Grumpy Cat, who explained marriage equality would make her happy.
Bert and Ernie showed up against the red background. (They're best friends with no plans to marry, according to Sesame Street.) Another version featured Paula Deen atop the red square and lines turned a shade of yellow akin to her favorite fatty ingredient and the tagline: "It's like two sticks of butter y'all."
Takei, a noted punster with nearly 4 million followers in Facebook, turned the equal sign into the division sign for those opposed to marriage equality.
Beyonce, with more than 44 million followers there, played it straight, leaving the logo alone and adding a personal message: "It's about TIME!!! (hash)EQUALITY (hash)MarryWhoYouLove.
Fergie let the image speak for itself on Twitter, adding: "No words necessary." Montana Sen. John Tester, a Democrat who endorsed same-sex marriage on Tuesday, put the logo up as his profile on Facebook while the clothing site Bonobos swapped its usual Facebook pic for the red square using fancy white pants for the equal sign.
Martha Stewart's Facebook page used a slice of red cake with white icing to make the image and the HBO page for "True Blood" added fangs.
All in good fun?
"There's a lot of serious conversation going on and there's an awful lot of important concepts that the Supreme Court justices are discussing," Sainz said. "What this logo going viral means is individuals have reduced it to a very straightforward concept."
Steve Jones, a professor of online culture and communications at the University of Illinois at Chicago, wondered whether all the mash-ups muddle the message.
"Once you throw it together with something like Grumpy Cat it's fun," he said. "But was this message intended to be fun?"
___
Associated Press writer Barbara Ortutay contributed to this report.
___
Follow Leanne Italie on Twitter at http://twitter.com/litalie
Source: http://news.yahoo.com/gay-marriage-equality-box-spreads-social-media-185401100.html
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Mali secular rebels appoint administrator in Kidal
OUAGADOUGOU, Burkina Faso (AP) ? A secular rebel group seeking independence in northern Mali said late Wednesday it has appointed a civil administrator for the region of Kidal, signaling it is retaking control of the government there as French forces battle radical Islamic fighters.
The National Movement for the Liberation of the Azawad, or NMLA, has been reasserting its presence in Kidal since the French-led intervention forced many of the extremists into the surrounding desert.
Mohamed Aly Ag Al Bessati was chosen Tuesday for the position, according to NMLA representative Moussa Ag Assarid.
"Today our priority is to protect people and property," he said. "These people need an administration to better lead activities and regain daily life."
The secular rebels have said they are willing to work with the French forces but not Malian troops, whom they accuse of committing reprisals against the lighter-skinned Tuaregs and Arabs.
"We can't entrust our destiny to any army that executes our families," Assarid said.
By comparison, Malian soldiers have bolstered the French presence in the northern cities of Gao and Timbuktu that also had been overrun by the radical Islamic fighters.
The Tuareg separatists who make up the NMLA have long sought independence from Mali, and their rebellion last year triggered a March coup in the distant capital.
In the aftermath, the Tuaregs and Islamic extremists had both made rapid advances across northern Mali and the poorly armed Malian soldiers fled.
For several months, the Islamic extremists controlling northern Mali coexisted with the secular Tuareg rebels who want their own state.
The black flag of the extremists fluttered alongside the multi-colored one of the secular rebels, each occupying different areas of the towns.
In late May 2012, the two sides attempted to sign a deal, agreeing to create an independent Islamic state called Azawad.
The agreement between the bon vivant Tuareg rebels and the Taliban-inspired extremists seemed doomed from the start. It fell apart days later. By June, the Islamic extremists had chased the secular rebels out of northern Mali's main cities.
However, a French-led military operation launched in mid-January forced the radical Islamists to flee northern Mali's major towns.
Source: http://news.yahoo.com/mali-secular-rebels-appoint-administrator-kidal-222804999.html
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Outsourcing Up, But Also Hiring in U.S. - IT Business Edge
Expect a surge in outsourcing this year, according to a new study from accounting and consulting firm BDO USA.
It found 63 percent of tech companies plan to outsource or manufacture products offshore this year, up from 35 percent in 2011 ? but manufacturing makes up a big chunk of that. Still, that?s the highest rate since it began the surveys in 2008.
Its findings are based on a poll of 100 U.S. technology chief financial officers, Fox Business notes.
At the same time, 43 percent plan to boost hiring in the United States. Thirty percent said they will be hiring in research and development this year, up from 23 percent last year and 22 percent in 2011.
According to Aftab Jamil, partner and director of the technology and life sciences practice at BDO USA:
?While the drive to remain competitive has led technology companies to maintain outsourcing contracts, many are working in tandem to grow their U.S. work force to develop new and innovative products and solutions in the U.S. while outsourcing traditional 'back office' operations.?
Meanwhile, HfS Research reports that IT outsourcing, while able to cut costs and standardize processes, is failing to deliver on the goals of providing innovation and access to analytics as well as transforming organizations.
Phil Fersht, founder and CEO, writes in his Horses for Sources blog that IT outsourcing isn?t expected to get much better, though some companies are bringing some IT work back to the United States. Low-end work is outsourced, high-end work is retained. And Ferscht told me that companies might be totally happy with that -- that they don?t want to spend more on functions such as help desk and systems maintenance and may accept less-than-stellar service in those areas.
Writes Fersht:
?Ambitious CIOs these days like to focus their time on ecommerce,?mobility, ?Big Data? and?cloud strategies, and will engage IT?consultants with projects?when they need some high-end help, but most aren?t expecting their outsourcer to do that kind of work for them. ??
The only way for service providers to move up the value chain, he says, is to provide services to meet defined business goals.
?Simply put, IT provides a supporting utility to help achieve these business outcomes that clients want to buy, which would ideally be accessible in the cloud where business users can access their services wherever they want. The focus then shifts from providing widgets, to the actual provision of value, where providers start working with their clients to achieve business results, as opposed to creating simply?a low-cost environment.?
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Monday, March 25, 2013
Ford apologizes for ads showing bound, gagged women
Ford Motor Co. is taking heat for a series of ads it released in India showing caricatures of several celebrities behind the wheel of a Ford car with three women bound and gagged in the cargo bay.
With critics declaring the campaign offensive and misogynistic, Ford and its global ad agency WPP have quickly backtracked, apologizing and admitting the campaign ?should never have happened.?
In one of the three images, released to the website Ads of the World, a cartoon Paris Hilton winks from behind the wheel of a Ford Figo with the three Kardashian sisters tied up in the cargo compartment of the hatchback. Another ad uses a satirical image of Italy?s former Prime Minister Silvio Berlusconi driving with three other scantily clad women, who were bound and gagged.
An ad for the Figo puts Formula One driving champ Michael Schumacher behind the wheel. In this one, however, three of his long-time (male) rivals are tied up: Sebastian Vettel, Lewis Hamilton and Fernando Alonso.
The WPP campaign appears to have been designed to show the large cargo capacity of the small Figo, a car Ford has hoped will help it gain a large share of the booming Indian automotive market.
?We deeply regret this incident and agree with our agency partners that it should have never happened,? Ford said in a statement responding to criticism. ?The posters are contrary to the standards of professionalism and decency within Ford and our agency partners.?
WPP added that the ads ?were distasteful and contrary to the standards of professionalism and decency.? The agency?s statement hinted that the three ads were originally created for in-house use and, ?were never intended for paid publication and should never have been created, let alone uploaded to the Internet.?
Whether intentionally made public, the ad campaign is unusual considering Ford has traditionally avoided generating controversy with its advertising. The maker responded to a conservative protest campaign a few years ago by pulling its advertising from gay, lesbian and bisexual publications ? although Ford later decided to resume that campaign.
It?s unclear what impact the ads ? and the apology ? will have on sales in India where the Figo has been gaining significant traffic since its launch in 2011. Ford has invested about $1 billion in that market since then, with the Figo anchoring the roll-out of eight new models.
Ironically, the controversy could generate more interest in the Ford line at a time when sexual violence has become an issue of national concern in India. Several high-profile gang rapes, including one earlier this month targeting a Swiss tourist, led the Indian Parliament last week to approve a new anti-rape law.
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Florida Gulf Coast University Enjoying Win Over Georgetown, Wants CBS To Get Name Right
Wichita State vs. Gonzaga
Carl Hall #22 of the Wichita State Shockers dunks the ball in the first half while taking on the Gonzaga Bulldogs during the third round of the 2013 NCAA Men's Basketball Tournament at EnergySolutions Arena on March 23, 2013 in Salt Lake City, Utah. (Photo by Harry How/Getty Images)
Wichita State vs. Gonzaga
Carl Hall #22 of the Wichita State Shockers steals the ball from Gary Bell, Jr. #5 of the Gonzaga Bulldogs alongside Demetric Williams #5 of the Shockers in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at EnergySolutions Arena on March 23, 2013 in Salt Lake City, Utah. (Photo by Harry How/Getty Images)
Wichita State vs. Gonzaga
Demetric Williams #5 of the Wichita State Shockers and Kevin Pangos #4 of the Gonzaga Bulldogs go after a loose ball in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at EnergySolutions Arena on March 23, 2013 in Salt Lake City, Utah. (Photo by Streeter Lecka/Getty Images)
Wichita State vs. Gonzaga
Kevin Pangos #4 of the Gonzaga Bulldogs reacts in the first half while taking on the Wichita State Shockers during the third round of the 2013 NCAA Men's Basketball Tournament at EnergySolutions Arena on March 23, 2013 in Salt Lake City, Utah. (Photo by Harry How/Getty Images)
Wichita State vs. Gonzaga
Kelly Olynyk #13 of the Gonzaga Bulldogs drives to the basket against Ehimen Orukpe #21 and Carl Hall #22 of the Wichita State Shockers in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at EnergySolutions Arena on March 23, 2013 in Salt Lake City, Utah. (Photo by Streeter Lecka/Getty Images)
Wichita State vs. Gonzaga
Ron Baker #31 of the Wichita State Shockers and Elias Harris #20 of the Gonzaga Bulldogs go after a loose ball in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at EnergySolutions Arena on March 23, 2013 in Salt Lake City, Utah. (Photo by Streeter Lecka/Getty Images)
Wichita State vs. Gonzaga
Carl Hall #22 of the Wichita State Shockers and Kelly Olynyk #13 of the Gonzaga Bulldogs go after a loose ball in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at EnergySolutions Arena on March 23, 2013 in Salt Lake City, Utah. (Photo by Streeter Lecka/Getty Images)
Wichita State vs. Gonzaga
Cleanthony Early #11 of the Wichita State Shockers blocks Sam Dower #35 of the Gonzaga Bulldogs in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at EnergySolutions Arena on March 23, 2013 in Salt Lake City, Utah. (Photo by Harry How/Getty Images)
Wichita State vs. Gonzaga
Cleanthony Early #11 of the Wichita State Shockers reacts after making a three-pointer in the first half against the Gonzaga Bulldogs during the third round of the 2013 NCAA Men's Basketball Tournament at EnergySolutions Arena on March 23, 2013 in Salt Lake City, Utah. (Photo by Streeter Lecka/Getty Images)
Wichita State vs. Gonzaga
Carl Hall #22 of the Wichita State Shockers dunks the ball in the first half while taking on the Gonzaga Bulldogs during the third round of the 2013 NCAA Men's Basketball Tournament at EnergySolutions Arena on March 23, 2013 in Salt Lake City, Utah. (Photo by Harry How/Getty Images)
Wichita State vs. Gonzaga
Ron Baker #31 of the Wichita State Shockers and Elias Harris #20 of the Gonzaga Bulldogs go after a loose ball in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at EnergySolutions Arena on March 23, 2013 in Salt Lake City, Utah. (Photo by Streeter Lecka/Getty Images)
Wichita State vs. Gonzaga
Carl Hall #22 and Cleanthony Early #11 of the Wichita State Shockers react after Early makes a three-pointer in the first half against the Gonzaga Bulldogs during the third round of the 2013 NCAA Men's Basketball Tournament at EnergySolutions Arena on March 23, 2013 in Salt Lake City, Utah. (Photo by Streeter Lecka/Getty Images)
Wichita State vs. Gonzaga
Mike Hart #30 of the Gonzaga Bulldogs and Carl Hall #22 of the Wichita State Shockers go after a loose ball in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at EnergySolutions Arena on March 23, 2013 in Salt Lake City, Utah. (Photo by Streeter Lecka/Getty Images)
Butler vs. Marquette
Trent Lockett #22 of the Marquette Golden Eagles dives for the ball against Kellen Dunham #24 of the Butler Bulldogs in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Butler vs. Marquette
Trent Lockett #22 of the Marquette Golden Eagles grabs a loose ball against Roosevelt Jones #21 of the Butler Bulldogs in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Butler vs. Marquette
Head coach Buzz Williams of the Marquette Golden Eagles looks on from the sideline in the first half against the Butler Bulldogs during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Butler vs. Marquette
Andrew Smith #44 of the Butler Bulldogs drives to the basket and draws a foul against Davante Gardner #54 of the Marquette Golden Eagles in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Butler vs. Marquette
Junior Cadougan #5 of the Marquette Golden Eagles shoots against Kellen Dunham #24 of the Butler Bulldogs in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Andy Lyons/Getty Images)
Butler vs. Marquette
Andrew Smith #44 of the Butler Bulldogs reacts after a play against the Marquette Golden Eagles in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Andy Lyons/Getty Images)
Butler vs. Marquette
Derrick Wilson #12 and Trent Lockett #22 of the Marquette Golden Eagles celebrate after a defensive play in the first half against the Butler Bulldogs during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Andy Lyons/Getty Images)
Butler vs. Marquette
Rotnei Clarke #15 of the Butler Bulldogs reacts after making a basket against the Marquette Golden Eagles in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Butler vs. Marquette
Jamil Wilson #0 of the Marquette Golden Eagles reacts after having a foul called on him in the first half against the Butler Bulldogs during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Butler vs. Marquette
Head coach Brad Stevens of the Butler Bulldogs talks to his players after a double flagrant foul in the first half against the Marquette Golden Eagles during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Butler vs. Marquette
Jamil Wilson #0 of the Marquette Golden Eagles handles the ball against Roosevelt Jones #21 of the Butler Bulldogs in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Oregon vs. Saint Louis
Cody Ellis #24 is called for a foul as he and Jordair Jett #5 of the Saint Louis Billikens defend against Johnathan Loyd #10 of the Oregon Ducks in the second half during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Ezra Shaw/Getty Images)
Oregon vs. Saint Louis
Cody Ellis #24 of the Saint Louis Billikens drives past Carlos Emory #33 of the Oregon Ducks in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Ezra Shaw/Getty Images)
Oregon vs. Saint Louis
Cody Ellis #24 of the Saint Louis Billikens and Arsalan Kazemi #14 of the Oregon Ducks vie for posession in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Ezra Shaw/Getty Images)
Oregon vs. Saint Louis
The Oregon Ducks bench reacts in the first half against the Saint Louis Billikens during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Thearon W. Henderson/Getty Images)
Oregon vs. Saint Louis
Arsalan Kazemi #14 passes the ball to Damyean Dotson #21 of the Oregon Ducks on a fast break in the first half against the Saint Louis Billikens during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Ezra Shaw/Getty Images)
Oregon vs. Saint Louis
Rob Loe #51 of the Saint Louis Billikens goes up against the Oregon Ducks in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Thearon Henderson/Getty Images)
Oregon vs. Saint Louis
Arsalan Kazemi #14 of the Oregon Ducks drives against Cody Ellis #24 of the Saint Louis Billikens in the fist half during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Ezra Shaw/Getty Images)
Oregon vs. Saint Louis
Head coach Jim Crews talks to Kwamain Mitchell #3 and Grandy Glaze #1 of the Saint Louis Billikens in the first half against the Oregon Ducks during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Ezra Shaw/Getty Images)
Oregon vs. Saint Louis
Kwamain Mitchell #3 of the Saint Louis Billikens drives against Arsalan Kazemi #14 of the Oregon Ducks in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Ezra Shaw/Getty Images)
Oregon vs. Saint Louis
E.J. Singler #25 of the Oregon Ducks falls on Dwayne Evans #21 of the Saint Louis Billikens as Jordair Jett #5 of the Saint Louis Billikens recovers the loose ball in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Ezra Shaw/Getty Images)
Oregon vs. Saint Louis
Grandy Glaze #1 of the Saint Louis Billikens drives against Tony Woods #55 of the Oregon Ducks in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Thearon Henderson/Getty Images)
Oregon vs. Saint Louis
Arsalan Kazemi #14 of the Oregon Ducks rebounds over Grandy Glaze #1 of the Saint Louis Billikens in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Ezra Shaw/Getty Images)
Oregon vs. Saint Louis
Tony Woods #55 of the Oregon Ducks goes up for a shot over Rob Loe #51 of the Saint Louis Billikens in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Ezra Shaw/Getty Images)
Oregon vs. Saint Louis
Head coach Dana Altman (L) and assistant coach Tony Stubblefield of the Oregon Ducks react in the first half against the Saint Louis Billikens during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Ezra Shaw/Getty Images)
Oregon vs. Saint Louis
Damyean Dotson #21 of the Oregon Ducks goes up against the Saint Louis Billikens in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Ezra Shaw/Getty Images)
Oregon vs. Saint Louis
Mike McCall Jr. #11 of the Saint Louis Billikens guards Johnathan Loyd #10 of the Oregon Ducks in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Thearon Henderson/Getty Images)
Oregon vs. Saint Louis
Arsalan Kazemi #14 of the Oregon Ducks rebounds over Grandy Glaze #1 of the Saint Louis Billikens in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Ezra Shaw/Getty Images)
Colorado State vs. Louisville
Kevin Ware #5 of the Louisville Cardinals defends Wes Eikmeier #10 of the Colorado State Rams in the second half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Andy Lyons/Getty Images)
Colorado State vs. Louisville
Colton Iverson #45 of the Colorado State Rams looks on in the first half agaisnt the Louisville Cardinals during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Colorado State vs. Louisville
Peyton Siva #3 of the Louisville Cardinals falls trying to dribble around Colton Iverson #45 of the Colorado State Rams in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Colorado State vs. Louisville
Montrezl Harrell #24 of the Louisville Cardinals takes a charge as Colton Iverson #45 of the Colorado State Rams goes up for a dunk in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Colorado State vs. Louisville
Colton Iverson #45 of the Colorado State Rams handles the ball against Stephan Van Treese #44 of the Louisville Cardinals in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Colorado State vs. Louisville
Montrezl Harrell #24 of the Louisville Cardinals reacts after a play against the Colorado State Rams in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Colorado State vs. Louisville
Dorian Green #22 of the Colorado State Rams celebrates after making a three point basket against the Louisville Cardinals in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Colorado State vs. Louisville
Colton Iverson #45 of the Colorado State Rams looks up after being poked in the eye in the first half against the Louisville Cardinals during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Colorado State vs. Louisville
Peyton Siva #3 of the Louisville Cardinals steals the ball from Greg Smith #44 of the Colorado State Rams in the second half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Colorado State vs. Louisville
Colton Iverson #45 of the Colorado State Rams handles the ball and is fouled by Gorgui Dieng #10 of the Louisville Cardinals in the second half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Source: http://www.huffingtonpost.com/2013/03/24/florida-gulf-coast-university-name-cbs_n_2944798.html
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Scientists unravel genetic code of esophageal cancer | The Raw Story
By Agence France-Presse
Sunday, March 24, 2013 14:52 EDT
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Scientists said Sunday they had found mutations in 26 genes that may cause oesophageal cancer, a breakthrough they hope will lead to new drugs for the deadly and increasingly frequent disease.
A team of experts in the United States unravelled the genetic code of tumour cells from 149 patients, which they compared to healthy cells to identify a mutation signature for oesophageal adenocarcinoma (EAC).
This type of cancer of the oesophagus or gullet, the muscular tube that moves food from the mouth to the stomach, has a five-year survival rate of only about 15-20 percent.
EAC often originates from a disease called Barrett?s oesophagus, which in turn is caused by chronic acid reflux.
Incidence of the cancer has increased by 600 percent over the last 30 years ? particularly in Western countries, according to the study.
Oesophageal cancer kills about 15,000 people in the United States alone every year ? and a total 400,000 worldwide.
Now, the biggest genetic analysis yet of this type of cancer has revealed common mutations that may be specifically targeted by new drugs.
?Finding the mutations helps us understand what makes the cancer tick,? study co-author Adam Bass of the Harvard Medical School told AFP.
?It can also help us find new therapies.?
Cancer develops when a human cell?s DNA is mutated so that its normal function is disrupted and it starts growing and spreading out of control.
There are different causes, including obesity, smoking, exposure to the sun?s UV rays or environmental pollution.
Mutations of different genes have been implicated in different cancers, but there are also vast differences even among people with the same form of the disease.
?We looked at which genes were mutated more frequently than would be expected by chance,? said Bass.
?Doing so, we found 26 genes that may be contributing to this cancer type.?
Genes are segments of DNA that carry the instruction manuals for cells.
The team found a frequent repetition of one particular type of mutation, suggesting it may be caused by some sort of exposure ? perhaps linked to acid reflux disease.
?Why this is especially interesting is that the rates of oesophageal adenocarcinoma have risen greatly in the last several decades,? said Bass.
?We suspect that there may be some factor in the reflux which is causing this specific type of DNA damage.
?If this is so and we can pin down what type of specific factor is responsible for these mutations, we may be able to develop new approaches to prevent these cancers or at least to diagnose them at an earlier point.?
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[DNA illustration via mathagraphics / Shutterstock]
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Source: http://www.rawstory.com/rs/2013/03/24/scientists-unravel-genetic-code-of-oesophageal-cancer/
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