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Friday, March 29, 2013
Xbox SmartGlass Will Be Your BFF While Watching Game of Thrones
Thursday, March 28, 2013
Gay marriage equality box spreads on social media
NEW YORK (AP) ? Bud Light said it with beer cans and Martha Stewart with red velvet cake as companies and celebrities from Beyonce to George Takei joined millions of social media users in posting and tweaking a simple red logo in support of gay marriage.
A square box with thick pink horizontal lines (the mathematical equal symbol) was offered for sharing this week by the Human Rights Campaign as the U.S. Supreme Court took up arguments in key marriage rights cases.
The image, replacing profile pictures on Facebook, Twitter, Instagram, Tumblr, Pinterest and elsewhere, is a makeover of the advocacy group's logo, usually a blue background with bright yellow lines. The HRC made it available in red ? for the color of love ? on Monday and estimated tens of millions of shares by Wednesday.
"It shows the enthusiasm and the passion," said Fred Sainz, a spokesman for the nonprofit in Washington, D.C.
Like viral campaigns of yore, supporting breast cancer awareness (pink), President Barack Obama (change your middle name to Hussein) and even Arab Spring (green), a bit of fatigue set in on some social media streams by those questioning whether such efforts serve to change any minds or, put simply, are plain annoying.
"My Facebook feed is a cascading aesthetic nightmare. Thanks, equality," Washington Post writer Dan Zak wryly grumbled on Twitter.
A photo of Justice Anthony Kennedy made the rounds with the quip: "Before we make a ruling, did enough people change their Facebook profile picture?!"
None of that mattered to the masses of same-sex marriage supporters. Some swapped matzoh for the pink lines as Passover got under way, or added frowny Internet star Grumpy Cat, who explained marriage equality would make her happy.
Bert and Ernie showed up against the red background. (They're best friends with no plans to marry, according to Sesame Street.) Another version featured Paula Deen atop the red square and lines turned a shade of yellow akin to her favorite fatty ingredient and the tagline: "It's like two sticks of butter y'all."
Takei, a noted punster with nearly 4 million followers in Facebook, turned the equal sign into the division sign for those opposed to marriage equality.
Beyonce, with more than 44 million followers there, played it straight, leaving the logo alone and adding a personal message: "It's about TIME!!! (hash)EQUALITY (hash)MarryWhoYouLove.
Fergie let the image speak for itself on Twitter, adding: "No words necessary." Montana Sen. John Tester, a Democrat who endorsed same-sex marriage on Tuesday, put the logo up as his profile on Facebook while the clothing site Bonobos swapped its usual Facebook pic for the red square using fancy white pants for the equal sign.
Martha Stewart's Facebook page used a slice of red cake with white icing to make the image and the HBO page for "True Blood" added fangs.
All in good fun?
"There's a lot of serious conversation going on and there's an awful lot of important concepts that the Supreme Court justices are discussing," Sainz said. "What this logo going viral means is individuals have reduced it to a very straightforward concept."
Steve Jones, a professor of online culture and communications at the University of Illinois at Chicago, wondered whether all the mash-ups muddle the message.
"Once you throw it together with something like Grumpy Cat it's fun," he said. "But was this message intended to be fun?"
___
Associated Press writer Barbara Ortutay contributed to this report.
___
Follow Leanne Italie on Twitter at http://twitter.com/litalie
Source: http://news.yahoo.com/gay-marriage-equality-box-spreads-social-media-185401100.html
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Mali secular rebels appoint administrator in Kidal
OUAGADOUGOU, Burkina Faso (AP) ? A secular rebel group seeking independence in northern Mali said late Wednesday it has appointed a civil administrator for the region of Kidal, signaling it is retaking control of the government there as French forces battle radical Islamic fighters.
The National Movement for the Liberation of the Azawad, or NMLA, has been reasserting its presence in Kidal since the French-led intervention forced many of the extremists into the surrounding desert.
Mohamed Aly Ag Al Bessati was chosen Tuesday for the position, according to NMLA representative Moussa Ag Assarid.
"Today our priority is to protect people and property," he said. "These people need an administration to better lead activities and regain daily life."
The secular rebels have said they are willing to work with the French forces but not Malian troops, whom they accuse of committing reprisals against the lighter-skinned Tuaregs and Arabs.
"We can't entrust our destiny to any army that executes our families," Assarid said.
By comparison, Malian soldiers have bolstered the French presence in the northern cities of Gao and Timbuktu that also had been overrun by the radical Islamic fighters.
The Tuareg separatists who make up the NMLA have long sought independence from Mali, and their rebellion last year triggered a March coup in the distant capital.
In the aftermath, the Tuaregs and Islamic extremists had both made rapid advances across northern Mali and the poorly armed Malian soldiers fled.
For several months, the Islamic extremists controlling northern Mali coexisted with the secular Tuareg rebels who want their own state.
The black flag of the extremists fluttered alongside the multi-colored one of the secular rebels, each occupying different areas of the towns.
In late May 2012, the two sides attempted to sign a deal, agreeing to create an independent Islamic state called Azawad.
The agreement between the bon vivant Tuareg rebels and the Taliban-inspired extremists seemed doomed from the start. It fell apart days later. By June, the Islamic extremists had chased the secular rebels out of northern Mali's main cities.
However, a French-led military operation launched in mid-January forced the radical Islamists to flee northern Mali's major towns.
Source: http://news.yahoo.com/mali-secular-rebels-appoint-administrator-kidal-222804999.html
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Outsourcing Up, But Also Hiring in U.S. - IT Business Edge
Expect a surge in outsourcing this year, according to a new study from accounting and consulting firm BDO USA.
It found 63 percent of tech companies plan to outsource or manufacture products offshore this year, up from 35 percent in 2011 ? but manufacturing makes up a big chunk of that. Still, that?s the highest rate since it began the surveys in 2008.
Its findings are based on a poll of 100 U.S. technology chief financial officers, Fox Business notes.
At the same time, 43 percent plan to boost hiring in the United States. Thirty percent said they will be hiring in research and development this year, up from 23 percent last year and 22 percent in 2011.
According to Aftab Jamil, partner and director of the technology and life sciences practice at BDO USA:
?While the drive to remain competitive has led technology companies to maintain outsourcing contracts, many are working in tandem to grow their U.S. work force to develop new and innovative products and solutions in the U.S. while outsourcing traditional 'back office' operations.?
Meanwhile, HfS Research reports that IT outsourcing, while able to cut costs and standardize processes, is failing to deliver on the goals of providing innovation and access to analytics as well as transforming organizations.
Phil Fersht, founder and CEO, writes in his Horses for Sources blog that IT outsourcing isn?t expected to get much better, though some companies are bringing some IT work back to the United States. Low-end work is outsourced, high-end work is retained. And Ferscht told me that companies might be totally happy with that -- that they don?t want to spend more on functions such as help desk and systems maintenance and may accept less-than-stellar service in those areas.
Writes Fersht:
?Ambitious CIOs these days like to focus their time on ecommerce,?mobility, ?Big Data? and?cloud strategies, and will engage IT?consultants with projects?when they need some high-end help, but most aren?t expecting their outsourcer to do that kind of work for them. ??
The only way for service providers to move up the value chain, he says, is to provide services to meet defined business goals.
?Simply put, IT provides a supporting utility to help achieve these business outcomes that clients want to buy, which would ideally be accessible in the cloud where business users can access their services wherever they want. The focus then shifts from providing widgets, to the actual provision of value, where providers start working with their clients to achieve business results, as opposed to creating simply?a low-cost environment.?
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Monday, March 25, 2013
Ford apologizes for ads showing bound, gagged women
Ford Motor Co. is taking heat for a series of ads it released in India showing caricatures of several celebrities behind the wheel of a Ford car with three women bound and gagged in the cargo bay.
With critics declaring the campaign offensive and misogynistic, Ford and its global ad agency WPP have quickly backtracked, apologizing and admitting the campaign ?should never have happened.?
In one of the three images, released to the website Ads of the World, a cartoon Paris Hilton winks from behind the wheel of a Ford Figo with the three Kardashian sisters tied up in the cargo compartment of the hatchback. Another ad uses a satirical image of Italy?s former Prime Minister Silvio Berlusconi driving with three other scantily clad women, who were bound and gagged.
An ad for the Figo puts Formula One driving champ Michael Schumacher behind the wheel. In this one, however, three of his long-time (male) rivals are tied up: Sebastian Vettel, Lewis Hamilton and Fernando Alonso.
The WPP campaign appears to have been designed to show the large cargo capacity of the small Figo, a car Ford has hoped will help it gain a large share of the booming Indian automotive market.
?We deeply regret this incident and agree with our agency partners that it should have never happened,? Ford said in a statement responding to criticism. ?The posters are contrary to the standards of professionalism and decency within Ford and our agency partners.?
WPP added that the ads ?were distasteful and contrary to the standards of professionalism and decency.? The agency?s statement hinted that the three ads were originally created for in-house use and, ?were never intended for paid publication and should never have been created, let alone uploaded to the Internet.?
Whether intentionally made public, the ad campaign is unusual considering Ford has traditionally avoided generating controversy with its advertising. The maker responded to a conservative protest campaign a few years ago by pulling its advertising from gay, lesbian and bisexual publications ? although Ford later decided to resume that campaign.
It?s unclear what impact the ads ? and the apology ? will have on sales in India where the Figo has been gaining significant traffic since its launch in 2011. Ford has invested about $1 billion in that market since then, with the Figo anchoring the roll-out of eight new models.
Ironically, the controversy could generate more interest in the Ford line at a time when sexual violence has become an issue of national concern in India. Several high-profile gang rapes, including one earlier this month targeting a Swiss tourist, led the Indian Parliament last week to approve a new anti-rape law.
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Florida Gulf Coast University Enjoying Win Over Georgetown, Wants CBS To Get Name Right
Wichita State vs. Gonzaga
Carl Hall #22 of the Wichita State Shockers dunks the ball in the first half while taking on the Gonzaga Bulldogs during the third round of the 2013 NCAA Men's Basketball Tournament at EnergySolutions Arena on March 23, 2013 in Salt Lake City, Utah. (Photo by Harry How/Getty Images)
Wichita State vs. Gonzaga
Carl Hall #22 of the Wichita State Shockers steals the ball from Gary Bell, Jr. #5 of the Gonzaga Bulldogs alongside Demetric Williams #5 of the Shockers in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at EnergySolutions Arena on March 23, 2013 in Salt Lake City, Utah. (Photo by Harry How/Getty Images)
Wichita State vs. Gonzaga
Demetric Williams #5 of the Wichita State Shockers and Kevin Pangos #4 of the Gonzaga Bulldogs go after a loose ball in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at EnergySolutions Arena on March 23, 2013 in Salt Lake City, Utah. (Photo by Streeter Lecka/Getty Images)
Wichita State vs. Gonzaga
Kevin Pangos #4 of the Gonzaga Bulldogs reacts in the first half while taking on the Wichita State Shockers during the third round of the 2013 NCAA Men's Basketball Tournament at EnergySolutions Arena on March 23, 2013 in Salt Lake City, Utah. (Photo by Harry How/Getty Images)
Wichita State vs. Gonzaga
Kelly Olynyk #13 of the Gonzaga Bulldogs drives to the basket against Ehimen Orukpe #21 and Carl Hall #22 of the Wichita State Shockers in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at EnergySolutions Arena on March 23, 2013 in Salt Lake City, Utah. (Photo by Streeter Lecka/Getty Images)
Wichita State vs. Gonzaga
Ron Baker #31 of the Wichita State Shockers and Elias Harris #20 of the Gonzaga Bulldogs go after a loose ball in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at EnergySolutions Arena on March 23, 2013 in Salt Lake City, Utah. (Photo by Streeter Lecka/Getty Images)
Wichita State vs. Gonzaga
Carl Hall #22 of the Wichita State Shockers and Kelly Olynyk #13 of the Gonzaga Bulldogs go after a loose ball in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at EnergySolutions Arena on March 23, 2013 in Salt Lake City, Utah. (Photo by Streeter Lecka/Getty Images)
Wichita State vs. Gonzaga
Cleanthony Early #11 of the Wichita State Shockers blocks Sam Dower #35 of the Gonzaga Bulldogs in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at EnergySolutions Arena on March 23, 2013 in Salt Lake City, Utah. (Photo by Harry How/Getty Images)
Wichita State vs. Gonzaga
Cleanthony Early #11 of the Wichita State Shockers reacts after making a three-pointer in the first half against the Gonzaga Bulldogs during the third round of the 2013 NCAA Men's Basketball Tournament at EnergySolutions Arena on March 23, 2013 in Salt Lake City, Utah. (Photo by Streeter Lecka/Getty Images)
Wichita State vs. Gonzaga
Carl Hall #22 of the Wichita State Shockers dunks the ball in the first half while taking on the Gonzaga Bulldogs during the third round of the 2013 NCAA Men's Basketball Tournament at EnergySolutions Arena on March 23, 2013 in Salt Lake City, Utah. (Photo by Harry How/Getty Images)
Wichita State vs. Gonzaga
Ron Baker #31 of the Wichita State Shockers and Elias Harris #20 of the Gonzaga Bulldogs go after a loose ball in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at EnergySolutions Arena on March 23, 2013 in Salt Lake City, Utah. (Photo by Streeter Lecka/Getty Images)
Wichita State vs. Gonzaga
Carl Hall #22 and Cleanthony Early #11 of the Wichita State Shockers react after Early makes a three-pointer in the first half against the Gonzaga Bulldogs during the third round of the 2013 NCAA Men's Basketball Tournament at EnergySolutions Arena on March 23, 2013 in Salt Lake City, Utah. (Photo by Streeter Lecka/Getty Images)
Wichita State vs. Gonzaga
Mike Hart #30 of the Gonzaga Bulldogs and Carl Hall #22 of the Wichita State Shockers go after a loose ball in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at EnergySolutions Arena on March 23, 2013 in Salt Lake City, Utah. (Photo by Streeter Lecka/Getty Images)
Butler vs. Marquette
Trent Lockett #22 of the Marquette Golden Eagles dives for the ball against Kellen Dunham #24 of the Butler Bulldogs in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Butler vs. Marquette
Trent Lockett #22 of the Marquette Golden Eagles grabs a loose ball against Roosevelt Jones #21 of the Butler Bulldogs in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Butler vs. Marquette
Head coach Buzz Williams of the Marquette Golden Eagles looks on from the sideline in the first half against the Butler Bulldogs during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Butler vs. Marquette
Andrew Smith #44 of the Butler Bulldogs drives to the basket and draws a foul against Davante Gardner #54 of the Marquette Golden Eagles in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Butler vs. Marquette
Junior Cadougan #5 of the Marquette Golden Eagles shoots against Kellen Dunham #24 of the Butler Bulldogs in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Andy Lyons/Getty Images)
Butler vs. Marquette
Andrew Smith #44 of the Butler Bulldogs reacts after a play against the Marquette Golden Eagles in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Andy Lyons/Getty Images)
Butler vs. Marquette
Derrick Wilson #12 and Trent Lockett #22 of the Marquette Golden Eagles celebrate after a defensive play in the first half against the Butler Bulldogs during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Andy Lyons/Getty Images)
Butler vs. Marquette
Rotnei Clarke #15 of the Butler Bulldogs reacts after making a basket against the Marquette Golden Eagles in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Butler vs. Marquette
Jamil Wilson #0 of the Marquette Golden Eagles reacts after having a foul called on him in the first half against the Butler Bulldogs during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Butler vs. Marquette
Head coach Brad Stevens of the Butler Bulldogs talks to his players after a double flagrant foul in the first half against the Marquette Golden Eagles during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Butler vs. Marquette
Jamil Wilson #0 of the Marquette Golden Eagles handles the ball against Roosevelt Jones #21 of the Butler Bulldogs in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Oregon vs. Saint Louis
Cody Ellis #24 is called for a foul as he and Jordair Jett #5 of the Saint Louis Billikens defend against Johnathan Loyd #10 of the Oregon Ducks in the second half during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Ezra Shaw/Getty Images)
Oregon vs. Saint Louis
Cody Ellis #24 of the Saint Louis Billikens drives past Carlos Emory #33 of the Oregon Ducks in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Ezra Shaw/Getty Images)
Oregon vs. Saint Louis
Cody Ellis #24 of the Saint Louis Billikens and Arsalan Kazemi #14 of the Oregon Ducks vie for posession in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Ezra Shaw/Getty Images)
Oregon vs. Saint Louis
The Oregon Ducks bench reacts in the first half against the Saint Louis Billikens during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Thearon W. Henderson/Getty Images)
Oregon vs. Saint Louis
Arsalan Kazemi #14 passes the ball to Damyean Dotson #21 of the Oregon Ducks on a fast break in the first half against the Saint Louis Billikens during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Ezra Shaw/Getty Images)
Oregon vs. Saint Louis
Rob Loe #51 of the Saint Louis Billikens goes up against the Oregon Ducks in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Thearon Henderson/Getty Images)
Oregon vs. Saint Louis
Arsalan Kazemi #14 of the Oregon Ducks drives against Cody Ellis #24 of the Saint Louis Billikens in the fist half during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Ezra Shaw/Getty Images)
Oregon vs. Saint Louis
Head coach Jim Crews talks to Kwamain Mitchell #3 and Grandy Glaze #1 of the Saint Louis Billikens in the first half against the Oregon Ducks during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Ezra Shaw/Getty Images)
Oregon vs. Saint Louis
Kwamain Mitchell #3 of the Saint Louis Billikens drives against Arsalan Kazemi #14 of the Oregon Ducks in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Ezra Shaw/Getty Images)
Oregon vs. Saint Louis
E.J. Singler #25 of the Oregon Ducks falls on Dwayne Evans #21 of the Saint Louis Billikens as Jordair Jett #5 of the Saint Louis Billikens recovers the loose ball in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Ezra Shaw/Getty Images)
Oregon vs. Saint Louis
Grandy Glaze #1 of the Saint Louis Billikens drives against Tony Woods #55 of the Oregon Ducks in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Thearon Henderson/Getty Images)
Oregon vs. Saint Louis
Arsalan Kazemi #14 of the Oregon Ducks rebounds over Grandy Glaze #1 of the Saint Louis Billikens in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Ezra Shaw/Getty Images)
Oregon vs. Saint Louis
Tony Woods #55 of the Oregon Ducks goes up for a shot over Rob Loe #51 of the Saint Louis Billikens in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Ezra Shaw/Getty Images)
Oregon vs. Saint Louis
Head coach Dana Altman (L) and assistant coach Tony Stubblefield of the Oregon Ducks react in the first half against the Saint Louis Billikens during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Ezra Shaw/Getty Images)
Oregon vs. Saint Louis
Damyean Dotson #21 of the Oregon Ducks goes up against the Saint Louis Billikens in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Ezra Shaw/Getty Images)
Oregon vs. Saint Louis
Mike McCall Jr. #11 of the Saint Louis Billikens guards Johnathan Loyd #10 of the Oregon Ducks in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Thearon Henderson/Getty Images)
Oregon vs. Saint Louis
Arsalan Kazemi #14 of the Oregon Ducks rebounds over Grandy Glaze #1 of the Saint Louis Billikens in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at HP Pavilion on March 23, 2013 in San Jose, California. (Photo by Ezra Shaw/Getty Images)
Colorado State vs. Louisville
Kevin Ware #5 of the Louisville Cardinals defends Wes Eikmeier #10 of the Colorado State Rams in the second half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Andy Lyons/Getty Images)
Colorado State vs. Louisville
Colton Iverson #45 of the Colorado State Rams looks on in the first half agaisnt the Louisville Cardinals during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Colorado State vs. Louisville
Peyton Siva #3 of the Louisville Cardinals falls trying to dribble around Colton Iverson #45 of the Colorado State Rams in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Colorado State vs. Louisville
Montrezl Harrell #24 of the Louisville Cardinals takes a charge as Colton Iverson #45 of the Colorado State Rams goes up for a dunk in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Colorado State vs. Louisville
Colton Iverson #45 of the Colorado State Rams handles the ball against Stephan Van Treese #44 of the Louisville Cardinals in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Colorado State vs. Louisville
Montrezl Harrell #24 of the Louisville Cardinals reacts after a play against the Colorado State Rams in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Colorado State vs. Louisville
Dorian Green #22 of the Colorado State Rams celebrates after making a three point basket against the Louisville Cardinals in the first half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Colorado State vs. Louisville
Colton Iverson #45 of the Colorado State Rams looks up after being poked in the eye in the first half against the Louisville Cardinals during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Colorado State vs. Louisville
Peyton Siva #3 of the Louisville Cardinals steals the ball from Greg Smith #44 of the Colorado State Rams in the second half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Colorado State vs. Louisville
Colton Iverson #45 of the Colorado State Rams handles the ball and is fouled by Gorgui Dieng #10 of the Louisville Cardinals in the second half during the third round of the 2013 NCAA Men's Basketball Tournament at Rupp Arena on March 23, 2013 in Lexington, Kentucky. (Photo by Kevin C. Cox/Getty Images)
Source: http://www.huffingtonpost.com/2013/03/24/florida-gulf-coast-university-name-cbs_n_2944798.html
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Scientists unravel genetic code of esophageal cancer | The Raw Story
By Agence France-Presse
Sunday, March 24, 2013 14:52 EDT
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Scientists said Sunday they had found mutations in 26 genes that may cause oesophageal cancer, a breakthrough they hope will lead to new drugs for the deadly and increasingly frequent disease.
A team of experts in the United States unravelled the genetic code of tumour cells from 149 patients, which they compared to healthy cells to identify a mutation signature for oesophageal adenocarcinoma (EAC).
This type of cancer of the oesophagus or gullet, the muscular tube that moves food from the mouth to the stomach, has a five-year survival rate of only about 15-20 percent.
EAC often originates from a disease called Barrett?s oesophagus, which in turn is caused by chronic acid reflux.
Incidence of the cancer has increased by 600 percent over the last 30 years ? particularly in Western countries, according to the study.
Oesophageal cancer kills about 15,000 people in the United States alone every year ? and a total 400,000 worldwide.
Now, the biggest genetic analysis yet of this type of cancer has revealed common mutations that may be specifically targeted by new drugs.
?Finding the mutations helps us understand what makes the cancer tick,? study co-author Adam Bass of the Harvard Medical School told AFP.
?It can also help us find new therapies.?
Cancer develops when a human cell?s DNA is mutated so that its normal function is disrupted and it starts growing and spreading out of control.
There are different causes, including obesity, smoking, exposure to the sun?s UV rays or environmental pollution.
Mutations of different genes have been implicated in different cancers, but there are also vast differences even among people with the same form of the disease.
?We looked at which genes were mutated more frequently than would be expected by chance,? said Bass.
?Doing so, we found 26 genes that may be contributing to this cancer type.?
Genes are segments of DNA that carry the instruction manuals for cells.
The team found a frequent repetition of one particular type of mutation, suggesting it may be caused by some sort of exposure ? perhaps linked to acid reflux disease.
?Why this is especially interesting is that the rates of oesophageal adenocarcinoma have risen greatly in the last several decades,? said Bass.
?We suspect that there may be some factor in the reflux which is causing this specific type of DNA damage.
?If this is so and we can pin down what type of specific factor is responsible for these mutations, we may be able to develop new approaches to prevent these cancers or at least to diagnose them at an earlier point.?
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[DNA illustration via mathagraphics / Shutterstock]
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Source: http://www.rawstory.com/rs/2013/03/24/scientists-unravel-genetic-code-of-oesophageal-cancer/
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Monday, March 11, 2013
International Women's Day - Morocco World News
By Sahar Amarir
Morocco World News
Paris, March 10, 2013
The road to hell is paved with good intentions, and while trying to make things right we might very often only make them worse without even realizing we do so. Friday was, as we all know, the international women?s day which couldn?t illustrate the saying any better. Everywhere in the media and on social networks one could see the enthusiasm, read the welter of passionate love declaration to women, of praising of women?s greatness, achievements and nature coming both from men and women, happily rejoicing at the idea that this is ?our day?, congratulating each other with nice wishes.
While witnessing this passionate expression of women?s sanctity, I felt like a total stranger to it watching it like a spectator would watch a theater play, knowing this is a comedy, already knowing how the story ends and that after the actors finish turning their life to art, everyone just goes back to their daily and usual lives.
But oddly enough, this feels like it was the right way to see it, because I am a feminist, and I feel nothing but frustration and exasperation on that day. Beyond the fact that I?m upset with the reality of women?s struggle that led to the very existence of that day ? thus showing that if women?s rights were correctly achieved, we wouldn?t even need it- it is its uses and misuses that further irritates me. ?International Women?s Day could be the opportunity to help societies move forward by efficiently deepening actions aiming at helping women in their struggles.
But instead, it has become a day for the society to purge its intentional ignorance of women?s issue the rest of the year by blowing its own trumpet on how aware of women?s struggle it is, since it even dedicates a day to it. But actually, that day is solely used to make statements void of genuine will of progress to hide the obvious deep disdain of the cause showing all year long?
This is the official catharsis day for sexists around the world, when they can finally externalize their ?best? jokes that would sound too harsh the rest of the year, when they can express what they seriously think while trying to brush it off with a humoristic tone, claiming we?ll be legit when speaking about equality the day we?ll be able to do what men do. Of course, those same people would never make jokes on disabled people on their international day, nor on minorities on fight against racism day, nor on the victims of a genocide on holocaust remembrance day for example.
Only women get to be treated this way and witness a display of typical sexist speeches wrapped up with hypocrite humor as a gift on Women?s Day.
Moreover, their argument shows a deep ignorance of the feminist cause and is even more ridiculous once you realize there are even more things women can do and that men can?t. More importantly, we know that we were born with a different physiognomy, we?re not identical and we certainly do not want to be identical to men.
However, we simply believe being born with this physiognomy doesn?t mean we shouldn?t have equal rights and equal opportunities in life. It does not mean we should be used as sexual or plastic objects. Nor does it mean we can be harassed, sexually assaulted because we are women, nor we accept to be paid less than a man because we are women, nor we will accept any gender based discrimination, nor we will accept on this day what we don?t accept the rest of the year: sexism. Apparently, it also seems to be the day women congratulate themselves over how much of an amazing creation of human life we are, that we deserve respect, It is also a day in which medias briefly recall some numbers: domestic violence, rapes, gender discrimination, wage gap.
To further improve progress and ensure the respect of women?s rights, these important numbers deserve to be published, denounced, analyzed, and explained more than just one time in the year. We need to get out of self-congratulations and from some media?s lip service to women?s rights, and make people realize that the fight of women?s rights exists throughout the year. Unfortunately, we were trapped in a day that makes the feminist cause one to be simply reminded for 24 hours, not worked on 365 days. While being half of the population ? and soon even more as we have a population turning older while women tend to live longer than men- we are still treated like a minority.
After all, minorities have their own day, but they are not half of the population. Neither are disabled people. And we were fooled into accepting to have a day dedicated to us, thus clearly showing the everlasting ostracism we are victim of in every society, no matter how many we are and no matter how much we work for the well-being of society. Looking more closely at this tragicomedy and all its actors, I already know the end: I see women?s rights have been in many ways trapped in a gilded cage with this day, people speaking about it on one day to forget about it the day after, and the rest of the year. But lest we forget, we have been imprisoned in certain ways many times, and the past generations worked hard to get us closer to freedom, and so shall we. Society can keep this day for another cause: we don?t want a road leading us to a hell of disinterest and ignorance. We need no day, no praises, no flowers, no sweet words or grandiloquent speeches. We need, we want and we ask for change. Not just a day, but every time, everywhere and for all of us.
Sahar Amarir is a student in Law and Political Sciences currently living in Paris, engaged in activism and interested in gender, minority and human rights issues.
The views expressed in this article are the author?s own and do not necessarily reflect Morocco World News? editorial policy
? Morocco World News. All Rights Reserved. This material may not be published, rewritten or redistributed
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Researchers solve riddle of what has been holding two unlikely materials together
Mar. 11, 2013 ? For years, researchers have developed thin films of bismuth telluride (Bi2Te3) -- which converts heat into electricity or electricity to cooling -- on top of gallium arsenide (GaAs) to create cooling devices for electronics. But while they knew it could be done, it was not clear how -- because the atomic structures of those unlikely pair of materials do not appear to be compatible. Now researchers from North Carolina State University and RTI International have solved the mystery, opening the door to new research in the field.
"We've used state-of-the-art technology to solve a mystery that has been around for years," says Dr. James LeBeau, an assistant professor of materials science and engineering at NC State and co-author of a paper on the research. "And now that we know what is going on, we can pursue research to fine-tune the interface of these materials to develop more efficient mechanisms for converting electricity to cooling or heat into electricity. Ultimately, this could have applications in a wide range of electronic devices."
To study the phenomenon, the researchers had to create the nanometer-scale thin films on a GaAs substrate, or foundation. The GaAs is first placed in a vapor deposition chamber. Molecules containing bismuth and tellurium are then introduced into the chamber, where they react with each other and "grow" into a crystalline Bi2Te3 structure on the surface of the GaAs.
Using advanced "Super-X" X-ray spectroscopy technology in conjunction with an aberration-corrected scanning transmission electron microscope, the researchers were able to determine what was binding the Bi2Te3 to the GaAs -- and it was not what they were expecting.
They found that when the tellurium molecules were introduced to the vapor deposition chamber, the tellurium reacted with the GaAs substrate to create a new surface layer of gallium telluride, which was only one molecule thick. The Bi2Te3 then formed a thin film on top of that new surface layer.
Because gallium telluride does not react with Bi2Te3, the research team knew chemical bonding could not be holding them together. Instead, the two layers are held together by the weaker force of van der Waals bonds -- meaning the materials are held together by weak electrical forces.
"While these materials have been investigated previously by RTI and NC State, the state-of-the-art techniques applied by LeBeau and his team have revealed significant new insights into how the film grows," notes Dr. Rama Venkatasubramanian of RTI International, who is also a co-author of the paper.
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The above story is reprinted from materials provided by North Carolina State University.
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Journal Reference:
- J. Houston Dycus, Ryan M. White, Jonathan M. Pierce, Rama Venkatasubramanian, James M. LeBeau. Atomic scale structure and chemistry of Bi2Te3/GaAs interfaces grown by metallorganic van der Waals epitaxy. Applied Physics Letters, 2013; 102 (8): 081601 DOI: 10.1063/1.4793518
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Cardinals say Mass, seek prayers ahead of conclave
U.S. Cardinal Sean Patrick O'Malley arrives to his titular church of Santa Maria alla Vittoria in Rome to celebrate Mass, Sunday, March 10, 2013. Cardinals from around the world gather this week in a conclave to elect a new pope following the stunning resignation of Benedict XVI. In the secretive world of the Vatican, there is no way to know who is in the running, and history has yielded plenty of surprises. Yet several names have come up time repeatedly as strong contenders for the job. O'Malley, the archbishop of Boston, is among those considered to have a credible shot at the papacy. (AP Photo/Domenico Stinellis)
U.S. Cardinal Sean Patrick O'Malley arrives to his titular church of Santa Maria alla Vittoria in Rome to celebrate Mass, Sunday, March 10, 2013. Cardinals from around the world gather this week in a conclave to elect a new pope following the stunning resignation of Benedict XVI. In the secretive world of the Vatican, there is no way to know who is in the running, and history has yielded plenty of surprises. Yet several names have come up time repeatedly as strong contenders for the job. O'Malley, the archbishop of Boston, is among those considered to have a credible shot at the papacy. (AP Photo/Domenico Stinellis)
Cardinal Angelo Scola, of Italy, celebrates a mass in Rome's Santi Apostoli church, Sunday March 10, 2013. Cardinals from around the world gather this week in a conclave to elect a new pope following the stunning resignation of Benedict XVI. In the secretive world of the Vatican, there is no way to know who is in the running, and history has yielded plenty of surprises. Yet several names have come up time repeatedly as strong contenders for the job. Scola, the Archbishop of Milan, is among those considered to have a credible shot at the papacy. (AP Photo/Andrew Medichini)
Cardinal Odilo Pedro Scherer arrives to celebrate mass in the Sant' Andrea al Quirinale church, in Rome, Sunday March 10, 2013. Cardinals from around the world gather this week in a conclave to elect a new pope following the stunning resignation of Benedict XVI. In the secretive world of the Vatican, there is no way to know who is in the running, and history has yielded plenty of surprises. Yet several names have come up time repeatedly as strong contenders for the job. Scherer, the Archbishop of Sao Paulo, is among those considered to have a credible shot at the papacy. (AP Photo/Andrew Medichini)
Cardinal Peter Erdo, of Hungary, celebrates a mass in St. Balbina basilica in Rome, Sunday March 10, 2013. Cardinals from around the world gather this week in a conclave to elect a new pope following the stunning resignation of Benedict XVI. In the secretive world of the Vatican, there is no way to know who is in the running, and history has yielded plenty of surprises. Yet several names have come up time repeatedly as strong contenders for the job. Erdo, the Archbishop of Esztergom-Budapest, is among those considered to have a credible shot at the papacy. (AP Photo/Alessandra Tarantino)
VATICAN CITY (AP) ? Cardinals took a break from maneuvering ahead of this week's papal conclave to fan out across Rome and celebrate Sunday Mass at local parishes.
The worship services provided a chance to see the cardinals up close and hear them preach two days before they enter the conclave. Roman Catholics and others packed the churches, holding up cell phones to take photos and video.
The cardinals said Mass in their titular churches, the parishes that according to church tradition are assigned to them as clergy of Rome, creating a symbolic bond with the pope. The conclave, with 115 cardinal-electors, is scheduled to start Tuesday.
The cardinals have been holding meetings and informal gatherings ahead of electing a successor to Benedict XVI. Several church leaders acknowledged the historic moment at Mass.
"This Sunday is also special because today we prepare for the conclave," said Boston Cardinal Sean O'Malley, in his sermon at Holy Mary of Victory church. "Let us pray that the Holy Spirit illumines the church to choose a new pope who will confirm us in our faith and make more visible the love of the good shepherd."
The parish priest who introduced the cardinal was more direct, describing O'Malley as "humble, but decisive," and saying he hoped his next visit to the church would be as pontiff. The leading Italian newspaper, Corriere della Sera, has cited the Boston archbishop as a favorite, despite past resistance to the idea of a superpower pope.
Cardinal Angelo Scola of Milan, considered a top papal contender, distributed communion at Church of the Twelve Holy Apostles, and spoke on the mission of the church.
"It is to announce over and over again, even to the modern man who is so sophisticated but sometimes lost in the new millennium, to announce always and repeatedly that the Lord's mercy is a source of hope even in these difficult times," he said. Scola waved to well-wishers as he was driven away from the church.
At Church of St. Andrew at the Quirinal, a crowd greeted Brazilian Cardinal Odilo Pedro Scherer, considered Brazil's best hope of filling the papacy. Scherer, who lived in Rome as a young priest, shook hands and hugged the faithful before celebrating Mass. He asked for prayers for the church, calling this period "certainly a difficult time, but also a joyful one and full of hope."
At the relatively young age of 63, Scherer embraces new approaches for reaching nonbelievers, while upholding Catholic orthodoxy, including rejecting same-sex marriage. Scherer joined Twitter in 2011 and in his second tweet said: "If Jesus preached the gospel today, he would also use print media, radio, TV, the Internet and Twitter. Give Him a chance!"
Cardinal Peter Erdo, the archbishop of Esztergom-Budapest, said Mass at Basilica of Santa Balbina on the Aventine hill, where the first known Hungarian cardinal, Istvan Vancsa, was buried in the 13th century. Erdo, a canon lawyer and theologian, is considered a possible compromise candidate. He would be the second pontiff to come from eastern Europe, following Pope John Paul II.
"Let us all pray for the Conclave that will gather the day after tomorrow," Erdo said. "Let's call the Holy Spirit to descend upon the Holy Church."
Associated PressSaturday, March 9, 2013
Sistine Chapel chimney installed, Vatican prepares for new pope
On Saturday the chimney that signals the election of a new pope was installed on the top of the Sistine Chapel. Pope Benedict XVI's personal seal and fisherman's ring were also destroyed as the cardinals prepare for the start of the conclave Tuesday.
Media films inside the Sistine Chapel at the Vatican March 9. The conclave begins on Tuesday, with the sequestered cardinals using the chimney to tell the outside world whether or not they have chosen a new leader - black smoke signifying no decision and white smoke announcing a new pontiff.
Stefano Rellandini/Reuters
EnlargeFirefighters on Saturday installed the top of the Sistine Chapel chimney that will signal to the world that a new?pope?has been elected, as the Vatican took measures to definitively end Benedict XVI's pontificate.
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While construction workers prepared the interior of the frescoed Sistine Chapel for Tuesday's start of the conclave, officials elsewhere in the Apostolic Palace destroyed Benedict's fisherman's ring and the personal seals and stamps for official papers.
The act, coupled with Benedict's public resignation and pledge of obedience to the future?pope, is designed to signal a definitive end of his papacy so there is no doubt in the church that a new?pope?is in charge.
The developments all point toward the momentous decision soon to confront the Catholic Church: Tuesday's start of the conclave to elect a new?pope?to lead the world's 1.2 billion Catholics and try to solve the numerous problems facing the church.
The Vatican outlined the timeline for the balloting and confirmed that the bells of St. Peter's Basilica will ring once a?pope?has been elected. But Vatican officials also acknowledged that there is some uncertainty about the whole endeavor, given the difficulties in discerning the color of smoke that will snake out of the Sistine chimney ? black if no?pope?has been elected, white if a victor has emerged.
Vatican spokesman, the Rev. Federico Lombardi, laughed off concerns, saying that some "suspense" was all part of the beauty of the process.
"We're not going to send out text messages or SMS messages, you'll have to come and see," another Vatican spokesman, the Rev. Thomas Rosica, said.
For the sixth day, cardinals met behind closed doors to discuss the problems of the church and once again they discussed the work of the Holy See's offices "and how to improve it," according to Lombardi.
The Holy See's internal governance has been the major constant in these days of discussion, an indication that the revelations of corruption, political infighting and turf battles exposed by the leaks of papal documents last year are casting a very big shadow over this conclave.
While the cardinals ponder their choices, preparations for the vote continue.
On Saturday, a handful of firefighters climbed onto the Sistine Chapel's roof and installed the top of the chimney. Inside Michelangelo's frescoed masterpiece, construction workers staple-gunned the felt carpeting to the false floor that has been erected over the chapel's stone floor.
The false floor both evens out the steps of the chapel and hides the jamming equipment that has been installed to prevent any cellphone or eavesdropping devices from working. And in fact, on Saturday, cell phones had no reception in the chapel.
For such an important decision, the Sistine chimney is an awfully simple affair: a century-old cast iron stove where the voting ballot papers are burned, with a copper pipe out the top that snakes up the Sistine's frescoed walls, out the window and onto the chapel roof.
After years of confusion about whether the smoke was black or white, the Vatican in 2005 installed an auxiliary stove where fumigating cases are lit. The smoke from those cases ? black or white ? joins the burned ballot smoke out the chimney.
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Global Average Temperatures Are Close to 11,000-Year Peak
GETTING WARMER: Earth's temperatures (here seen by an infrared sensor on the NASA satellite Aqua) are on course to be as hot as at any time since the last ice age. Image: Image courtesy AIRS Science Team, NASA/JPL
Global average temperatures are now higher than they have been for about 75% of the past 11,300 years, a study suggests. And if climate models are any indication, by the end of this century they will be the highest ever since the end of the most recent ice age.
Instrumental records of climate extend back to only the late nineteenth century. Beyond that, scientists depend on analyses of natural chronicles such as tree rings and isotope ratios in cave formations.
But even these archives have their limits: many detailed reconstructions of climate, particularly of temperature, apply to only limited regions or extend back at most a couple of millennia, says Shaun Marcott, a climate scientist at Oregon State University in Corvallis.
Marcott and his colleagues set about reconstructing global climate trends all the way back to 11,300 years ago, when the Northern Hemisphere was emerging from the most recent ice age. To do so, they collected and analyzed data gathered by other teams. The 73 overlapping climate records that they considered included sediment cores drilled from lake bottoms and sea floors around the world, along with a handful of ice cores collected in Antarctica and Greenland.
Each of these chronicles spanned at least 6,500 years, and each included a millennium-long baseline period beginning in the middle of the post-ice-age period at 3550 BC.
For some records, the researchers inferred past temperatures from the ratio of magnesium and calcium ions in the shells of microscopic creatures that had died and dropped to the ocean floor; for others, they measured the lengths of long-chain organic molecules called alkenones that were trapped in the sediments.
After the ice age, they found, global average temperatures rose until they reached a plateau between 7550 and 3550 BC. Then a long-term cooling trend set in, reaching its lowest temperature extreme between ad 1450 and 1850.
Since then, temperatures have been increasing at a dramatic clip: from the first decade of the twentieth century to now, global average temperatures rose from near their coldest point since the ice age to nearly their warmest, Marcott and his team report today in Science.
Climate context
The temperature trends that the team identified for the past 2,000 years are statistically indistinguishable from results obtained by other researchers in a previous study, says Marcott. ?That gives us confidence that the rest of our record is right too,? he adds.
Marcott and his colleagues ?have put together a pretty impressive set of climate proxies?, says Gavin Schmidt, a climate scientist at the NASA Goddard Institute for Space Studies in New York. ?The overall climate picture has been clear for a long time, mostly from the Northern Hemisphere, but this compilation really puts the rest of the world in context,? he adds.
?Prior to this study, researchers could only guess whether global temperatures had exceeded the warmest part of the present interglacial period,? says Darrell Kaufman, a geologist at Northern Arizona University in Flagstaff. The latest findings show that the recent high temperatures are not necessarily the warmest, but they are unusually high, he notes.
Source: http://rss.sciam.com/click.phdo?i=86ed3cfe656ca023da6b6892536abddb
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Friday, March 8, 2013
WTF-Mini Titanium Keychain ? You wont need to curse to tighten that nut
Ever need a wrench in a pinch, but just don’t have one handy? The WTF-Mini Titanium Keychain (WTF stands for Wrench That Fits) can solve that problem. Although this ?Kickstarter project?is listed as a Titanium keychain, it will also be available in aluminum. The WTF measures 2.85 inches long and 0.83 inches wide; it weighs [...]
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Thursday, March 7, 2013
Disney working on standalone Star Wars movies
PHOENIX (AP) ? Star Wars fans have more than just Episodes 7, 8 and 9 to look forward to.
Disney CEO Bob Iger said at the annual shareholders meeting in Phoenix on Wednesday that the company is developing "some standalone movies" featuring Star Wars characters.
The news is likely to set off a new round of speculation about what's in store for the Lucasfilm franchise. The buzz has been at fever pitch levels since The Walt Disney Co. said in October it was acquiring the studio for $4 billion.
Iger didn't say which characters might be featured in the standalone films. Some Star Wars characters such as bounty hunter Boba Fett have been given bigger treatments in comic books.
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Explore Lomography Nearby - Maharashtra, India http://ow.ly/irAY0
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Bob Hope's iconic estate listed for $50 million
Palm Springs, Calif.
For sale: $50 million
Actor Bob Hope owned a collection of homes in Palm Springs and the L.A. area, and two have hit the market ? both snagging buyers within a month of listing. But the real prize of Hope's homes is the John Lautner-designed property, an architectural treasure that hit the market in late February for $50 million.
Architect John Lautner was well-known for his dramatic designs, and his biggest piece was a custom home for Bob and Dolores Hope. Perched in the private neighborhood of Southridge, the estate dominates a corner lot with sweeping views of the Coachella Valley.
Hope's 23,366-square-foot home was designed in 1973 by Lautner to resemble a volcano. The modernist structure is built of concrete and glass, with an undulating copper roof that rises to an open semi-circle at its center.
The home was used primarily as a second residence for the Hope family and was where they entertained most often, inviting friends such as crooner Tony Bennett and country music singer Glen Campbell to enjoy the views from the house.
Listed by Ann Eysenring of Partners Trust in Beverly Hills along with Patrick Jordan and Stewart Smith of Windermere Real Estate in Palm Springs, the home has six bedrooms and 12 baths. Outdoor spaces include a pool, pond, tennis court and outdoor fireplace.
The Lautner home is just the latest of the Hope estates to be listed; the final property, a custom home in Toluca Lake, Los Angeles used by the Hopes as their primary residence, has yet to be listed.
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Source: http://www.nbcnews.com/business/bob-hopes-iconic-estate-listed-50-million-1C8620900
15 Fitness Gadgets vs. One Personal Trainer
As yet, there is still no technological substitute for human willpower. But in the quest to get in shape, we flabby citizens have a long history of leaning on gadgets to get us up and active. The first pedometer design is attributed to Leo?nardo da Vinci, while Thomas Jefferson built his own such device to measure his walks. Since then vibrating belts, electric shocks, and sweaty sauna suits have been touted as high-tech routes to fitness. And in the 1980s, a former Viet Cong sympathizer leveraged the popularity of the VHS to turn herself into a domestic exercise icon with a series of workout tapes.
Believe it or not, Jane Fonda is still at it, finally upgrading to the DVD format in 2010. But her discs are lost in a sea of video games with motion-capture avatars that track your body movements and encourage/hector you in real time. And those games are just the tip of the high-tech-fitness iceberg, with a wide variety of gadgets that promise to inspire you to become a leaner, stronger, healthier you.
The gold standard for fitness coaching is the personal trainer?a real person certified as a professional exercise instructor. But hiring one can be extremely expensive?upwards of $60 per session, which could cause many clients to go broke before they get fit.
Can a bunch of high-tech doodads provide instruction and inspiration comparable to what you'd get from a trained professional? I donned my tracksuit and covered myself in sensors to find out.
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Monday, March 4, 2013
Misplaced molecules: New insights into the causes of dementia
Monday, March 4, 2013
A shortage of a protein called TDP-43 caused muscle wasting and stunted nerve cells. This finding supports the idea that malfunction of this protein plays a decisive role in ALS and FTD. The study is published in the "Proceedings of the National Academy of Sciences of the USA" (PNAS).
ALS is an incurable neurological disease which manifests as rapidly progressing muscle wasting. Both limbs and respiratory muscles are affected. This leads to impaired mobility and breathing problems. Patients commonly die within a few years after the symptoms emerged. In rare cases, of which the British physicist Stephen Hawking is the most notable, patients can live with the disease for a long time. In Germany estimates show over 150,000 patients suffering from ALS ? an average of 1 in 500 people.
Proteins gone astray
Over the last few years, there has been increasing evidence that ALS and FTD ? a form of dementia associated with changes in personality and social behaviour ? may have similar or even the same origins. The symptoms overlap and common factors have also been found at the microscopic level. In many cases, particles accumulate and form clumps in the patient's nerve cells: this applies particularly to the TDP-43 protein.
"Normally, this protein is located in the cell nucleus and is involved in processing genetic information," explains molecular biologist Dr. Bettina Schmid, who works at the DZNE Munich site and at LMU. "However, in cases of disease, TDP-43 accumulates outside the nucleus forming aggregates." Schmid explains that it is not yet clear whether these clumps are harmful. "However, the protein's normal function is clearly disrupted. It no longer reaches the nucleus to perform its actual task. There seems to be a relationship between this malfunction and the disease."
Studies on zebrafish
However, until now little was known about the function of TDP-43. What are the consequences when this protein becomes non-functional? In order to answer this question, the team led by Bettina Schmid cooperated with the research group of Prof. Christian Haass to investigate the larvae of specially bred zebrafish. Their genetic code had been modified in such a way that no TDP-43 was produced in the organism of the fish. The result: the young fish showed massive muscle wasting and died a few days after hatching. Moreover, the extensions of the nerve cells which control the muscles were abnormal.
"To some extent, these are symptoms typical of ALS and FTD. Therefore, a loss of function of TDP-43 does seem to play a critical role in the disease," says Haass, Site Speaker of the DZNE Munich Site and chair of Metabolic Biochemistry at LMU.
The study revealed one more finding which surprised the researchers: the blood flow of the fish was massively disturbed. "It is well known that circulatory disorders play a part in other forms of dementia, notably in the case of Alzheimer's," says Haass. "We now want to investigate whether such problems with blood flow may be a general problem of neurodegenerative diseases and whether such problems occur particularly in patients with ALS and FTD."
###
Helmholtz Association of German Research Centres: http://www.helmholtz.de/en/index.html
Thanks to Helmholtz Association of German Research Centres for this article.
This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.
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Source: http://www.labspaces.net/127105/Misplaced_molecules__New_insights_into_the_causes_of_dementia
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